Prevalence of Metallo Beta Lactamase Production among Bacterial Isolates in Cases of Neonatal Septicemia in HAHC Hospital, Delhi, India
نویسندگان
چکیده
Bacterial sepsis is one of the major causes of morbidity and mortality among neonates. It is characterized as generalized bacterial infection indicated by positive blood culture in the first four weeks of life (Agarwal et al., 2001). The common causative agents for neonatal sepsis are Staphylococcus spp, Enterococci spp, E. coli, Klebsiella spp, Enterobacter spp, Pseudomonas aeruginosa and Acinetobacter spp (Roy et al., 2002). Metallo-beta-lactamase is an enzyme that makes bacteria resistant to a broad range of beta-lactam antibiotics including Carbapenem family. The spread of these enzymes severely limits therapeutic options for infections by pathogens (Peleg et al., 2005).
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